Alpostin 500 Mcg Injection (Alprostadil)

Last Updated on 01/29/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav What Is Alpostin 500 Mcg Injection?Alpostin 500 mcg Injection contains Alprostadil (Prostaglandin E1) and is a prescription-only hospital medicine in Australia.Alpostin 500 mcg injection is an injection that is given to a male person with the ED or erectile dysfunction disorder. Having this disorder means that the person is not able to get a hard and strong erection.Even if you do not get a hard erection or wonder if you are not able to maintain it, there is no need to worry now. The Alpostin 500 mcg injection is there to give you a strong erection within just a few minutes.This is a new form of ED remedy where the doctors give you an injection into your muscles in the body that gets rid of any ED signs.What Is It Used For In Australia?In Australian clinical practice, alprostadil injections are used mainly to:Maintain patency of the ductus arteriosus in newborns with certain congenital heart defectsSupport blood circulation until corrective cardiac surgery can be performedThis use is specialist-directed and typically managed by neonatologists or paediatric cardiologists.Key PointsActive ingredient: Alprostadil (Prostaglandin E1)Strength: 500 micrograms (mcg)Composition: Alprostadil is a form of vasodilator medication that helps dilate the arteries.Manufacturer: Samarth Lifesciences Pvt. Ltd. has the exclusive rights to manufacture this medicine in India.Drug class: Vasodilator / ProstaglandinPrimary use: Keeps the ductus arteriosus open in newborns with congenital heart defectsRoute: Intravenous (IV) infusionSetting: Hospital use onlyOnset: Rapid action after infusion beginsMonitoring: Continuous monitoring of breathing, heart rate, and blood pressureCommon side effects: Apnoea, low blood pressure, fever, flushingPrescription: Specialist-prescribed (neonatology/paediatrics)Not for self-use: Must be administered by trained healthcare professionalsMethod Of Daily Use For Alpostin 500 Mcg InjectionDepending on your condition, you may not even have to use the Alpostin 500 mcg injection daily.A single use of the injection can last a few hours, given the amount of dose you are using.Only in case of a more severe ED, an issue not curable with other remedies used before, will the doctors tell you to take the Alpostin 500 mcg injection daily.However, since it is a kind of injection, it is always a good idea to take the help of the doctors to administer the vaccine in your body for proper use.How Does Alpostin 500 Mcg Injection Work?Relaxes smooth muscle in blood vesselsCauses vasodilation, improving blood flowKeeps the ductus arteriosus open in affected newbornsThe Alpostin 500 mcg injection works based on dilation.First, under the action of Alprostadil, the PDE-5 hormones are inhibited.This increases the affinity for the cGMP enzyme.It is here that nitric oxide gets active and starts producing its dilation effects.This is the effect where the blood vessels dilate or widen, giving more blood flow to the penis tissues.✓ How It Is GivenAdministered as an intravenous (IV) infusionGiven only in hospital settingsRequires continuous monitoring (heart rate, breathing, blood pressure)Alpostin 500 Mcg Injection- How Long Does It Last?Your erection after using the injection will last close to one to 2 hours easily.Typically, you get a hard erection within 30 minutes of using the vaccine.Is Alpostin 500 mcg Injection an effective injection?Yes, the Alpostin injection is more effective since the drug inside is injected directly into the bloodstream, which has a more direct action.Dosage Of Alpostin 500 Mcg Injection✓ For Mild ED ProblemsUse the Alpostin 500 mcg injection up to 3 to 4 times per week, keeping at least 24 hours between doses.The doctors can also give you a smaller strength, like the 250-mcg dose.✓ For Severe EDIn case of severe ED issues, the doctors can tell you to administer the injection daily.✓ What Happens If I Miss Taking A Dose?In case you miss taking your dose for even a single day, you may not get a hard erection during sex. Also, note that it reduces the action of the medicine in your body.✓ What Happens If I Overdose On This Medicine?The moreyour overdose, the higher the risk of severe side effects. Remember that the instructions for using the medicine are to always use the right dose. Excess Alprostadil can cause harmful effects in your body in the end.Alpostin 500 mcg Injection – Age-wise Dosage✓ Newborns / Neonates (Primary Use)Used to maintain ductus arteriosus patency in congenital heart defects.Starting dose:0.05–0.1 micrograms/kg/min (IV infusion)Maintenance dose:Reduced to 0.01–0.05 micrograms/kg/min once adequate response is achievedAdministration:Continuous intravenous infusionMonitoring required:Breathing (risk of apnoea), heart rate, blood pressure, oxygen levels✓ Infants & ChildrenUse is rare and highly specialisedDose is individualised by paediatric cardiology specialistsAlways given in a hospital setting✓ AdultsAlpostin 500 mcg injection is NOT typically used in adultsAlprostadil for adults (e.g., erectile dysfunction) uses different formulations and dosesBenefits Of Taking Alpostin 500 Mcg InjectionBy using the Alpostin 500 mcg injection, you now have a solution to get hard any time and have sex without any issues of losing or not getting hard.It typically helps you get erections faster than ED medicines.It has a more direct action, which ensures an erection even for severe ED problems.Precautions And Warnings✓ With AlcoholAlcohol and narcotic drugs are to be avoided. These can cause all forms of minor or sometimes even severe side effects.✓ DrivingPeople driving, especially those who have taken the Alpostin 500 mcg injection dose and start to feel dizziness or nausea, must avoid driving.Drug Interaction Classification✓ With Other MedicinesNitrate injectionsPDE-5 hormone blockersMedicines of the alpha and beta blocker categories✓ With Other Health IssuesThe doctors strictly do not recommend this medicine to patients with high BP, a major heart disorder, or right after heart surgery.✓ With FoodStudies even show that the use of Alpostin 500 mcg injection is not suitable for some types of food items. Earlier scientists have found some types of food that may cause interactions with the medicine and cause side effects. All these food items are high sources of nitrates.What Are The Side Effects Of Alpostin 500 Mcg Injection?✓ Common Side EffectsStomach painWeaknessesBloatingDiarrheaAllergic reactions at the site of injectionSkin rashesNauseaHeadacheDizzinessThese mild issues should only last for a few days and go away.✓ Severe Side EffectsChest painVision blurRise of BPPriapism✓ Precautions And WarningsThe standard dosage recommendation from the doctors is to use a single injection for daily use.The doctors will tell you how long you need to use this medicine.Keep using the medicine until the end of the tenure and do not stop taking it.Remember that each dose is able to give a temporary effect for a few hours.When To Seek Medical Help?Always take medical help from the doctors during consultation ofonour dose.Do not forget to have the doctors administer the right dose inside your body.Take medical help in case the current dose is not working properly for a few hours, and you want to increase the strength of the injection.Safety Advice Of Alpostin 500 Mcg Injection✓ In Case Of Allergic Side EffectsSome patients may be completely allergic to Alprostadil. In such a case, you can get side effects like-RashesItchingSwellingStop using the medicines due to such side effects.✓ For Males With EDTaking Alprostadil as a chief generic component is only for the sexual condition of ED in males. Each injection lasts for some timeduringn which you can get free of any ED symptoms.✓ Key Safety NotesNot for home useDose depends on weight, condition, and responseRisk of apnoea, especially in premature infantsRequires immediate access to respiratory supportStorage InstructionsStore the Alpostin 500 mcg injection in an area of low heat and humidity. It is better not to keep the medicine in the fridge or directly in the sunlight.For storage, always look for a safe and locked place in your house such that the sachet of medicines is protected from your child’s reach.Is Alpostin 500 Mcg Injection Legal In Sydney?Yes, it is legal to buy Alpostin 500 mcg injection in Sydney using a prescription after the TGA mandated its use for use in males with ED, but with a prescription only.Where To Buy Alpostin 500 Mcg Injection In Australia?To buy Alpostin 500 mcg injection in Australia, check out authorised websites that are approved by the TGA in Australia, like AustraliaRXMeds.In simple termsIn Australia, Alpostin 500 mcg Injection is a hospital-only medicine used to support critically ill newborns with heart defects by improving blood flow until surgery is possible.FAQsDuring Pregnancy, Can I Take Alpostin 500 Mcg Injection?No, this medicine is safe to use only in males who have ED. Whether you are pregnant, you should not use this injection since it is of no use to females.Is It Safe For Children To Take Alpostin 500 Mcg Injection?No, the minimum age someone has to be is 18 years or older.Is It Safe To Use This Injection With Skin Allergies?Do not apply it at the site of allergic infection,s or else you may have severe rashes and itching.Is Alprostadil Safe With Cancer Treatments?The doctors may not recommenthe d use of Alprostadil injections when you are undergoing any cancer treatment.How is Alpostin 500 mcg Injection given?Given as a continuous IV (intravenous) infusionAdministered only in hospital settingsRequires constant medical monitoringWho can receive Alpostin 500 mcg Injection?Primarily newborns and neonatesUse is decided by neonatologists or paediatric cardiologistsNot intended for routine adult useIs Alpostin 500 mcg Injection used for erectile dysfunction?No. Although alprostadil can be used for erectile dysfunction in adults, this strength and formulation are meant for neonatal cardiac care.